Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. A 2022 Clinical Practice Guideline from the American Association of Clinical Endocrinology and the American Association for the Study of Liver Diseases provides screening, diagnosis, and management algorithms for NAFLD.1 Early diagnosis in the primary care setting is important to reduce disease progression.
- Cusi K, Isaacs S, Barb D, et al. American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and endocrinology clinical settings: co-sponsored by the American Association for the Study of Liver Diseases (AASLD). Endocr Pract. 2022;28(5):528-562. doi:10.1016/j.eprac.2022.03.010.
- Ye Q, Zou B, Yeo YH, et al. Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2020;5(8):739-752. doi:10.1016/S2468-1253(20)30077-7.
- 3. Lomonaco R, Godinez Leiva E, Bril F, et al. Advanced liver fibrosis is common in patients with type 2 diabetes followed in the outpatient setting: the need for systematic screening. Diabetes Care. 2021;44(2):399-406. doi:10.1016/j.eprac.2022.03.010.doi:10.2337/dc20-1997.